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E-AB-19626

ENPP2 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-19626
Additional Names:
ATX,ATX X,Autotaxin,Autotaxin t,E NPP 2,E-NPP 2,ENPP2,Ectonucleotide pyrophosphatase/phosphodiesterase 2,Ectonucleotide pyrophosphatase/phosphodiesterase family member 2,Enpp2,Extracellular lysophospholipase D,FLJ26803,LysoPLD,NPP2,PD IALPHA,PDNP2,Phospho
Application:
IHC
Concentration:
0.8 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human ENPP2
Uniprot:
Q13822
Synonyms:
ATX;ATX-X;AUTOTAXIN;autotaxin-t;E-NPP 2;ectonucleotide pyrophosphatase/phosphodiesterase family member 2;extracellular lysophospholipase D;LysoPLD;NPP2;PD-IALPHA;PDNP2;phosphodiesterase I/nucleotide pyrophosphatase 2;plasma lysophospholipase D
Extra Details:
The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5&apos, end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.
Shipping Conditions:
Blue Ice