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E-AB-19507

IFNB1 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-19507
Additional Names:
Fibroblast interferon,IFB,IFF,IFN beta,IFN-beta,IFNB,IFNB 1,IFNB1,Interferon beta,Interferon beta 1 fibroblast,Interferon beta precursor,MGC96956,beta-interferon
Application:
IHC
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human IFNB1
Uniprot:
P01574
Synonyms:
fibroblast interferon;IFB;IFF;IFN-beta;IFNB;interferon beta;interferon-beta;interferon, beta 1, fibroblast
Extra Details:
This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection.
Shipping Conditions:
Blue Ice