E-AB-19397
BAG2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-19397
- Additional Names:
- BAG 2,BAG family molecular chaperone regulator 2,BAG-2,BAG-family molecular chaperone regulator-2,BAG2,BCL 2 associated athanogene 2,BCL2 associated athanogene 2,BCL2-associated athanogene 2,Bag2,Bcl-2-associated athanogene 2,dJ417I1.2 (BAG family molecul
- Application:
- IHC, WB
- Concentration:
- 0.9 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human BAG2
- Uniprot:
- O95816
- Synonyms:
- BAG family molecular chaperone regulator 2;BAG-2;bcl-2-associated athanogene 2;BCL2 associated athanogene 2;dJ417I1.2;dJ417I1.2 (BAG-family molecular chaperone regulator 2)
- Extra Details:
- BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
- Shipping Conditions:
- Blue Ice