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E-AB-19376

COX17 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-19376
Additional Names:
COX 17,COX17,COX17 cytochrome c oxidase assembly homolog,COX17 cytochrome c oxidase assembly homolog (S. cerevisiae),COX17 homolog cytochrome c oxidase assembly protein,Cytochrome c oxidase copper ,cytochrome c oxidase assembly protein cox17 homolog
Application:
IHC
Concentration:
1.2 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human COX17
Uniprot:
Q14061
Synonyms:
COX17 cytochrome c oxidase assembly homolog;COX17, cytochrome c oxidase copper chaperone;cytochrome c oxidase 17 copper chaperone;cytochrome c oxidase assembly homolog 17;cytochrome c oxidase copper chaperone;human homolog of yeast mitochondrial copper recruitment
Extra Details:
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen.This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes.The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex.This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme.This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins.This gene is no longer considered to be a candidate gene for COX deficiency.A pseudogene COX17P has been found on chromosome 13.
Shipping Conditions:
Blue Ice