E-AB-19341
HAS1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-19341
- Additional Names:
- HA synthase 1,HAS,HAS1,HYAS1,HuHAS1,Hyaluronan synthase 1,Hyaluronate synthase 1,Hyaluronic acid synthase 1
- Application:
- IHC
- Concentration:
- 0.96 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human HAS1
- Uniprot:
- Q92839
- Synonyms:
- HA synthase 1;HAS;hyaluronan synthase 1;hyaluronate synthase 1;hyaluronic acid synthase 1
- Extra Details:
- Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis.
- Shipping Conditions:
- Blue Ice