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E-AB-19340

GLS Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-19340
Additional Names:
AAD20,DKFZp686O15119,FLJ10358,GAC,GAM,GLS,GLS1,GLSK,Glutaminase C,Glutaminase kidney isoform,Glutaminase phosphate activated,K-glutaminase,KGA,KIAA0838,L-glutamine amidohydrolase,mitochondrial
Application:
IHC, WB
Concentration:
1.02 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human GLS
Uniprot:
O94925
Synonyms:
AAD20;CASGID;DEE71;EIEE71;GAC;GAM;GDPAG;GLS1;glutaminase C;glutaminase kidney isoform, mitochondrial;glutaminase, phosphate-activated;K-glutaminase;KGA;L-glutamine amidohydrolase
Extra Details:
GLS,also named as GLS1 and KIAA0838,belongs to the glutaminase family. It catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Glutaminase-,glutamate-,and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease.The glutaminase band in AA/C1 cells is more intense than in HT29 cells,in accordance with measurements of glutaminase activity,and had the same molecular mass of approx. 63 kDa. The bands for both cell lines are clearly different in size from both rat liver glutaminase (58 kDa) and rat kidney glutaminase (65 kDa). It also reveals a molecular weight of 83-84 kDa as a phosphate-dependent glutaminase. It has 3 isoforms named as KGA,GAM,GAC.
Shipping Conditions:
Blue Ice