E-AB-19239
MTHFD2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-19239
- Additional Names:
- Metabolism,Signal Transduction
- Application:
- IHC
- Concentration:
- 1.14 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human MTHFD2
- Uniprot:
- P13995
- Synonyms:
- bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial;NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase;NMDMC
- Extra Details:
- This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.
- Shipping Conditions:
- Blue Ice