PTPA Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:: E-AB-19232
Additional Names:: regulatory subunit B-prime,KIAA0044 ,MGC2184 ,PP2A,PP2A phosphatase activator ,PP2A subunit B',PP2A subunit B' PR53 isoform ,PP2A subunit B' isoform PR53,PPP2R4,PR53 ,PR53 isoform,Phosphotyrosyl phosphatase activator,Pro,Protein phosphatase 2,subunit B''
Application:: IHC
Concentration:: 0.84 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Fusion protein of human PTPA
Uniprot:: Q15257
Synonyms:: phosphotyrosyl phosphatase activator;PP2A;PP2A phosphatase activator;PP2A, subunit B', PR53 isoform;PPP2R4;PR53;protein phosphatase 2 regulatory subunit 4;protein phosphatase 2A activator, regulatory subunit 4;protein phosphatase 2A regulatory subunit 4;protein phosphatase 2A, regulatory subunit B' (PR 53);serine/threonine-protein phosphatase 2A activator;Serine/threonine-protein phosphatase 2A regulatory subunit 4;serine/threonine-protein phosphatase 2A regulatory subunit B'
Extra Details:: Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

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