E-AB-19169
MRPL40 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-19169
- Additional Names:
- 39S ribosomal protein L40,39S ribosomal protein L40 mitochondrial,FLJ41774,L40mt,MGC9400,MRP 40,MRP L22,MRP-L40,MRP40,MRPL22,MRPL40,Mitochondrial ribosomal protein L40,NLVCF,Nuclear localizat,mitochondrial,mitochondrial precursor
- Application:
- IHC, WB
- Concentration:
- 1.44 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human MRPL40
- Uniprot:
- Q9NQ50
- Synonyms:
- 39S ribosomal protein L40, mitochondrial;L40mt;mitochondrial large ribosomal subunit protein mL40;MRP-L22;MRP-L40;MRPL22;NLVCF;nuclear localization signal-containing protein deleted in velocardiofacial syndrome;up-regulated in metastasis;URIM
- Extra Details:
- Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.MRPL40 (Mitochondrial Ribosomal Protein L40) is a Protein Coding gene. Diseases associated with MRPL40 include Mrpl40-Related Disorder and Velocardiofacial Syndrome. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance. GO annotations related to this gene include poly(A) RNA binding.
- Shipping Conditions:
- Blue Ice