E-AB-19158
TMX3 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-19158
- Additional Names:
- member 13,KIAA1830,PDIA13,Protein disulfide isomerase family A,Protein disulfide-isomerase TMX3,TMX3,TXNDC10,Thioredoxin domain containing 10,Thioredoxin domain-containing protein 10,Thioredoxin-related transmembrane protein 3
- Application:
- IHC
- Concentration:
- 1.26 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human TMX3
- Uniprot:
- Q96JJ7
- Synonyms:
- PDIA13;protein disulfide isomerase family A, member 13;protein disulfide-isomerase TMX3;thioredoxin domain containing 10;thioredoxin domain-containing protein 10;Thioredoxin-related transmembrane protein 3;TXNDC10
- Extra Details:
- This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The canonical protein encoded by this gene has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This gene is expressed in many tissues but has its highest expression in heart and skeletal muscle. It is expressed in the retinal neuroepithelium and lens epithelium in the developing murine eye and haploinsufficiency of this gene in humans and zebrafish is associated with microphthalmia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Shipping Conditions:
- Blue Ice