E-AB-19027
FDPS Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-19027
- Additional Names:
- Dimethylallyltranstransferase,FPP synthase,FPP synthetase,FPPS,FPPS_HUMAN,FPS,Farnesyl diphosphate synthase,Farnesyl diphosphate synthetase,Farnesyl pyrophosphate synthase,Farnesyl pyrophosphate synthetase,Fdps,Geranyltranstransferase
- Application:
- IHC
- Concentration:
- 1.02 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human FDPS
- Uniprot:
- P14324
- Synonyms:
- (2E,6E)-farnesyl diphosphate synthase;Dimethylallyltranstransferase;Farnesyl diphosphate synthase;farnesyl pyrophosphate synthase;farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase;FPP synthase;FPP synthetase;FPPS;FPS;Geranyltranstransferase;POROK9
- Extra Details:
- This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice