E-AB-19022
SF3B3 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-19022
- Additional Names:
- KIAA0017,Pre mRNA splicing factor SF3b 130 kDa subunit,Pre-mRNA-splicing factor SF3b 130 kDa subunit,RSE1,SAP 130,SAP130,SF3B3,SF3B3_HUMAN,SF3b130,Spl,Spliceosome associated protein 130,Spliceosome-associated protein 130,Splicing factor 3b subunit 3 130kD
- Application:
- IHC
- Concentration:
- 1.2 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human SF3B3
- Uniprot:
- Q15393
- Synonyms:
- pre-mRNA splicing factor SF3b, 130 kDa subunit;Pre-mRNA-splicing factor SF3b 130 kDa subunit;RSE1;SAP 130;SAP130;SF3b130;spliceosome-associated protein 130;splicing factor 3B subunit 3;STAF130
- Extra Details:
- This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.
- Shipping Conditions:
- Blue Ice