E-AB-18994
SETMAR Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-18994
- Additional Names:
- Histone lysine N methyltransferase,Histone lysine N methyltransferase SETMAR,Hsmar 1,Hsmar1,Mariner transposase Hsmar1,Metnase,SET domain and mariner transposase fusi,SET domain and mariner transposase fusion,SET domain and mariner transposase fusion gene
- Application:
- IHC
- Concentration:
- 1.08 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human SETMAR
- Uniprot:
- Q53H47
- Synonyms:
- histone-lysine N-methyltransferase SETMAR;Mar1;METNASE;SET domain and mariner transposase fusion gene-containing protein;SET domain and mariner transposase fusion protein
- Extra Details:
- This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
- Shipping Conditions:
- Blue Ice