E-AB-18979
ECH1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-18979
- Additional Names:
- 4)-dienoyl-CoA isomerase,5)-Delta(2,Delta(3,Delta(3 5) Delta(2 4) dienoyl CoA isomerase,Delta(3 5) Delta(2 4) dienoyl CoA isomerase mitochondrial,Delta3 5 delta2 4 dienoyl CoA isomerase,Dienoyl CoA isomerase,ECH 1,ECH1,Ech1,En,Enoyl Coenzyme A hydratase 1
- Application:
- IHC, WB
- Concentration:
- 0.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human ECH1
- Uniprot:
- Q13011
- Synonyms:
- delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial;delta3,5-delta2,4-dienoyl-CoA isomerase;delta3,5-delta2,4-dienoyl-coenzyme A isomerase;dienoyl-CoA isomerase;enoyl Coenzyme A hydratase 1, peroxisomal;enoyl-CoA hydratase 1, peroxisomal;epididymis secretory sperm binding protein;HPXEL;peroxisomal enoyl-CoA hydratase 1
- Extra Details:
- This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.
- Shipping Conditions:
- Blue Ice