E-AB-18841
EXD2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-18841
- Additional Names:
- 4930539P14Rik,C14orf114,C85658,DKFZp781A0133,DKFZp781L15100,EXD2,EXDL2,Exd2,Exonuclease 3''-5'' domain-containing protein 2,Exonuclease 3''-5'' domain-like-containing protein 2,FLJ10738,RGD1311087,exonuclease 3'-5' domain-like 2
- Application:
- IHC, WB
- Concentration:
- 0.96 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human EXD2
- Uniprot:
- Q9NVH0
- Synonyms:
- 3'-5' exoribonuclease EXD2;C14orf114;EXDL2;exonuclease 3'-5' domain-containing protein 2;exonuclease 3'-5' domain-like 2;exonuclease 3'-5' domain-like-containing protein 2
- Extra Details:
- Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
- Shipping Conditions:
- Blue Ice