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E-AB-18801

MDFI Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-18801
Additional Names:
I MF,I mfa,Inhibitor of MyoD family a,MDFI,Mdfi,MyoD family inhibitor,Myogenic repressor I-mf,OTTHUMP00000016375,OTTHUMP00000016376,OTTHUMP00000196103,OTTHUMP00000196414,OTTHUMP00000196415
Application:
IHC, WB
Concentration:
0.96 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Fusion protein of human MDFI
Uniprot:
Q99750
Synonyms:
I-MF;I-mfa;inhibitor of MyoD family a;myoD family inhibitor;myogenic repressor I-mf
Extra Details:
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.MDFI (MyoD Family Inhibitor) is a Protein Coding gene. GO annotations related to this gene include transcription factor binding. An important paralog of this gene is MDFIC.
Shipping Conditions:
Blue Ice