E-AB-18785
ISCU Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-18785
- Additional Names:
- 2310020H20Rik,HML,ISCU,Iron sulfur cluster assembly enzyme ISCU mitochondrial,Iron sulfur cluster scaffold homolog,Iron sulfur cluster scaffold homolog (E. coli),Iron-sulfur cluster assembly enzyme ISCU,IscU iron sulfur cluster scaffold homolog,Iscu,hnifU
- Application:
- WB
- Concentration:
- 0.96 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human ISCU
- Uniprot:
- Q9H1K1
- Synonyms:
- 2310020H20Rik;HML;hnifU;iron-sulfur cluster assembly enzyme ISCU, mitochondrial;IscU iron-sulfur cluster scaffold homolog;ISU2;NIFU;nifU-like N-terminal domain-containing protein;NifU-like protein;NIFUN
- Extra Details:
- This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.
- Shipping Conditions:
- Blue Ice