E-AB-18766
C8orf4 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-18766
- Additional Names:
- C8orf4,CH004,Chromosome 8 open reading frame 4,Human thyroid cancer 1,MGC22806,TC-1,TC1,Thyroid cancer protein 1,Uncharacterized protein C8orf4
- Application:
- IHC
- Concentration:
- 0.96 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human C8orf4
- Uniprot:
- Q9NR00
- Synonyms:
- C8orf4;human thyroid cancer 1;protein C8orf4;TC-1;TC1;thyroid cancer protein 1;transcriptional and immune response regulator
- Extra Details:
- This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.
- Shipping Conditions:
- Blue Ice