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E-AB-18722

TP63 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-18722
Additional Names:
AIS,Amplified in squamous cell carcinoma,B(p51A),B(p51B),CUSP,Chronic ulcerative stomatitis protein,DN p63 alpha 1,DNp63,EEC3,KET,Keratinocyte transcription factor,Keratinocyte transcription factor KET,LMS,MGC115972,MGC192897,NBP,OFC8,OTTHUMP00,id:ibd3516
Application:
IHC
Concentration:
1.14 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Fusion protein of human TP63
Uniprot:
Q9H3D4
Synonyms:
AIS;amplified in squamous cell carcinoma;B(p51A);B(p51B);chronic ulcerative stomatitis protein;EEC3;keratinocyte transcription factor KET;KET;LMS;NBP;OFC8;p40;p51;p53CP;p63;p73H;p73L;RHS;SHFM4;TP53CP;TP53L;TP73L;transformation-related protein 63;tumor protein 63;tumor protein p53-competing protein;Tumor protein p73-like
Extra Details:
TP63,also named KET,P63,P73H,P73L and TP73L,belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53,the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor. TP63 has 12 isoforms with MW 40kd(P40),50kd(P60),63kd(P63) and 73kd(P73L). It is Nuclear stain.
Shipping Conditions:
Blue Ice