E-AB-18656
DENND1B Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-18656
- Additional Names:
- C1ORF18,C1orf218 ,Chromosome 1 open reading frame 218,Connecdenn 2,DEN1B,DENN MADD domain containing 1B,DENN domain containing protein 1B,DENN domain-containing protein 1B,DENND1B,DKFZp547O0715,FAM31B ,FLJ20054,Family with sequence similarity 31 member B
- Application:
- WB
- Concentration:
- 0.54 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human DENND1B
- Uniprot:
- Q6P3S1
- Synonyms:
- C1ORF18;C1orf218;connecdenn 2;DENN domain-containing protein 1B;DENN/MADD domain containing 1B;FAM31B;family with sequence similarity 31, member B;Protein FAM31B
- Extra Details:
- Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery.
- Shipping Conditions:
- Blue Ice