E-AB-18554
C12orf40 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-18554
- Additional Names:
- C12orf40,CL040,Chromosome 12 open reading frame 40,FLJ40126,Uncharacterized protein C12orf40
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human C12orf40
- Uniprot:
- Q86WS4
- Synonyms:
- epididymis luminal protein 206;epididymis secretory protein Li 94;HEL-206;HEL-S-94;uncharacterized protein C12orf40
- Extra Details:
- Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf40 gene product has been provisionally designated C12orf40 pending further characterization.
- Shipping Conditions:
- Blue Ice