E-AB-18525
ATXN3 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-18525
- Additional Names:
- AT3,ATX3,ATXN3,Ataxin 3,Ataxin-3,EC 3.4.22.,JOS,Josephin,Mac,Machado Joseph disease,Machado Joseph disease (spinocerebellar ataxia 3,ataxin 3 variant h,ataxin 3 variant m,ataxin 3 variant ref,ataxin 3),autosomal dominant,olivopontocerebellar ataxia 3
- Application:
- IHC
- Concentration:
- 0.7 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human ATXN3
- Uniprot:
- P54252
- Synonyms:
- AT3;ataxin-3;ATX3;JOS;josephin;Machado-Joseph disease protein 1;MJD;MJD1;olivopontocerebellar ataxia 3;SCA3;spinocerebellar ataxia type 3 protein
- Extra Details:
- Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Shipping Conditions:
- Blue Ice