E-AB-18519
USP14 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-18519
- Additional Names:
- Deubiquitinating enzyme 14,TGT,Ubiquitin carboxyl terminal hydrolase 14,Ubiquitin carboxyl-terminal hydrolase 14,Ubiquitin specific peptidase 14,Ubiquitin specific processing protea,tRNA guanine transglycosylase,tRNA guanine transglycosylase 60 kD subunit
- Application:
- WB
- Concentration:
- 0.7 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human USP14
- Uniprot:
- P54578
- Synonyms:
- deubiquitinating enzyme 14;TGT;tRNA-guanine transglycosylase, 60-kD subunit;ubiquitin carboxyl-terminal hydrolase 14;ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase);ubiquitin specific protease 14 (tRNA-guanine transglycosylase);ubiquitin thioesterase 14;ubiquitin thiolesterase 14;ubiquitin-specific processing protease 14;Ubiquitin-specific-processing protease 14
- Extra Details:
- This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
- Shipping Conditions:
- Blue Ice