E-AB-18486
WDFY2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-18486
- Additional Names:
- PROF,Propeller-FYVE protein,RP11 147H23.1,WD repeat and FYVE domain containing 2,WD repeat and FYVE domain-containing protein 2,WD40 and FYVE domain containing 2,WD40- and FYVE domain-containing protein 2,WDF2,WDFY2,Wdfy2,ZFYVE22,Zinc finger FYVE domain-c
- Application:
- IHC, WB
- Concentration:
- 0.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human WDFY2
- Uniprot:
- Q96P53
- Synonyms:
- PROF;propeller-FYVE protein;WD repeat and FYVE domain-containing protein 2;WD40 and FYVE domain containing 2;WD40- and FYVE domain-containing protein 2;WDF2;ZFYVE22;zinc finger FYVE domain-containing protein 22
- Extra Details:
- WD repeat and FYVE domain-containing protein 2 (WDFY2), also known as WDF2 and ZFYVE22, is a 400 amino acid protein that localizes to a set of small endosomes that are found within 100 nm from the plasma membrane. Highly conserved between species, WDFY2 consists of one FYVE-type zinc finger and seven WD repeats. The FYVE domain is a cysteine-rich domain of about 70 amino acids. Its primary role is to target signal-transducing proteins to cell membranes through binding to the membrane lipid phosphatidylinositol-3-phosphate with high specificity. WD-repeats are generally found in clusters of seven. They have no intrinsic catalytic activity, but they serve as a platform for protein-protein interactions. WDFY2 is suspected to play a critical role in the endocytic pathway.
- Shipping Conditions:
- Blue Ice