E-AB-18391
GRAP Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-18391
- Additional Names:
- GRAP,GRB2 related adaptor protein,GRB2-related adapter protein,Grap,Growth factor receptor bound protein 2 related adaptor protein,MGC64880,OTTHUMP00000065766
- Application:
- IHC
- Concentration:
- 0.7 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Full length fusion protein
- Uniprot:
- Q13588
- Synonyms:
- DFNB114;GRB2-related adapter protein;growth factor receptor-bound protein 2-related adaptor protein
- Extra Details:
- This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.
- Shipping Conditions:
- Blue Ice