E-AB-18375
IDO2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-18375
- Additional Names:
- 3 dioxygenase 2,3 dioxygenase l,3 dioxygenase like 1 protein,3 dioxygenase like protein 1,3-dioxygenase 2,3-dioxygenase-like protein 1,EC 1.13.11.,I23O2,IDO 2,IDO-2,INDOL 1,Ido2,Indoleamine 2,Indoleamine pyrrole 2
- Application:
- IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Full length fusion protein
- Uniprot:
- Q6ZQW0
- Synonyms:
- INDOL1;indoleamine 2,3-dioxygenase 2;indoleamine 2,3-dioxygenase-like 1 protein;indoleamine 2,3-dioxygenase-like protein 1;indoleamine-pyrrole 2,3 dioxygenase-like 1;indoleamine-pyrrole 2,3-dioxygenase-like protein 1
- Extra Details:
- INDOL1 is also known as IDO2 (indoleamine 2,3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2,3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1.
- Shipping Conditions:
- Blue Ice