ZNF486 Polyclonal Antibody

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£106.20

Was £118.00

SKU:: E-AB-18362
Additional Names:: KRAB box only protein 2 ,KRBO2 ,Zinc finger protein 486
Application:: IHC
Concentration:: 0.9 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Fusion protein of human ZNF486
Uniprot:: Q96H40
Synonyms:: KRAB box only protein 2;KRAB domain only 2;KRAB domain only protein 2;KRBO2;zinc finger protein 486
Extra Details:: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF486 (Zinc finger protein 486), also known as KRAB domain only protein 2, is a 216 amino acid nuclear protein that contains one KRAB domain and two C2H2-type zinc fingers. The gene encoding ZNF486 maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. May be involved in transcriptional regulation.