E-AB-18330
ATF6B Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-18330
- Additional Names:
- ATF6-beta,ATF6B,Activating transcription factor 6 beta,CREBL1,Cyclic AMP-dependent transcription factor ATF-6 beta,G13,Protein G13,cAMP response element-binding protein-related protein,cAMP-dependent transcription factor ATF-6 beta
- Application:
- IHC, WB
- Concentration:
- 0.5 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human ATF6B
- Uniprot:
- Q99941
- Synonyms:
- Activating transcription factor 6 beta;cAMP response element-binding protein-related protein;cAMP-dependent transcription factor ATF-6 beta;cAMP-responsive element-binding protein-like 1;Creb-related protein;CREB-RP;CREBL1;cyclic AMP-dependent transcription factor ATF-6 beta;G13;protein G13
- Extra Details:
- The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice