ABI2 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:: E-AB-18253
Additional Names:: ABI 2,ABI2,ABI2B,AIP 1,Abelson interactor 2,Abi-2,Abl binding protein 3,Abl interacting protein 1 (SH3 containing protein),Abl interactor 2,Abl interactor protein 2b,Abl-binding protein 3,AblBP3,Arg binding protein 1,Arg protein tyrosine kinase bindi
Application:: IHC
Concentration:: 0.78 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Fusion protein of human ABI2
Uniprot:: Q9NYB9
Synonyms:: abelson interactor 2;ABI-2;ABI2B;abl binding protein 3;abl interactor 2;Abl-binding protein 3;abl-interacting protein 1 (SH3-containing protein);abl-interactor protein 2b;AblBP3;AIP-1;AIP1;arg protein tyrosine kinase-binding protein;arg-binding protein 1;argBP1;argBPIA;argBPIB;SSH3BP2
Extra Details:: May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes.