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E-AB-18215

CBX5 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-18215
Additional Names:
Antigen p25,CBX5,CG8409,Chromobox 5,Chromobox homolog 5,Chromobox homolog 5 (HP1 alpha homolog,Chromobox protein homolog 5,Drosophila),Epididymis luminal protein 25,HEL25,Heterochromatin prote,Heterochromatin protein 1,Heterochromatin protein 1 alpha
Application:
WB
Concentration:
1.32 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Fusion protein of human CBX5
Uniprot:
P45973
Synonyms:
antigen p25;chromobox homolog 5 (HP1 alpha homolog, Drosophila);chromobox protein homolog 5;epididymis luminal protein 25;HEL25;heterochromatin protein 1 homolog alpha;heterochromatin protein 1-alpha;HP1;HP1 alpha homolog;HP1-ALPHA;HP1A;HP1Hs alpha
Extra Details:
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Shipping Conditions:
Blue Ice