E-AB-18214
CAPN6 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-18214
- Additional Names:
- CALP M,CAN6,CANP X,CANPX,CAPN 6,CalpM,Calpain-6,Calpain-like protease X-linked,Calpamodulin,Capn6
- Application:
- WB
- Concentration:
- 0.78 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human CAPN6
- Uniprot:
- Q9Y6Q1
- Synonyms:
- calpain-6;calpain-like protease X-linked;calpamodulin;CalpM;CANPX;CAPNX;DJ914P14.1
- Extra Details:
- Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.
- Shipping Conditions:
- Blue Ice