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E-AB-18204

CCNF Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-18204
Additional Names:
CCNF,Ccnf,Cyclin-F,F box only protein 1,F-box only protein 1,FBX1,FBXO1,G2 mitotic specific cyclin F,G2/mitotic specific cyclin F
Application:
IHC, WB
Concentration:
0.9 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human CCNF
Uniprot:
P41002
Synonyms:
cyclin-F;F-box only protein 1;FBX1;FBXO1;FTDALS5;G2/mitotic-specific cyclin-F
Extra Details:
This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified.
Shipping Conditions:
Blue Ice