E-AB-18142
MAPK8IP3 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-18142
- Additional Names:
- C-jun-amino-terminal kinase-interacting protein 3,FLJ00027,Homolog of Drosophila Sunday driver 2,JIP-3,JIP3,JNK / Stress Activated Protein Kinase Associated Protein 1,JNK Interacting Protein 3,JNK MAP kinase scaffold protein 3,JNK-interacting protein
- Application:
- IHC
- Concentration:
- 1.26 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human MAPK8IP3
- Uniprot:
- Q9UPT6
- Synonyms:
- C-jun-amino-terminal kinase interacting protein 3;C-Jun-amino-terminal kinase-interacting protein 3;homolog of Drosophila Sunday driver 2;JIP-3;JIP3;JNK MAP kinase scaffold protein 3;JNK-interacting protein 3;JNK/SAPK-associated protein-1;JNK/stress-activated protein kinase-associated protein 1;JSAP1;Mitogen-activated protein kinase 8-interacting protein 3;NEDBA;syd;SYD2
- Extra Details:
- The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. MAPK8IP3 (Mitogen-Activated Protein Kinase 8 Interacting Protein 3) is a Protein Coding gene. Among its related pathways are MAPK signaling pathway and Arf6 trafficking events. GO annotations related to this gene include kinesin binding and receptor signaling complex scaffold activity. An important paralog of this gene is SPAG9.
- Shipping Conditions:
- Blue Ice