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E-AB-18110

IL37 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-18110
Additional Names:
FIL,IL1F,IL1H,IL-1F,IL1RP,IL-1RP,IL37,FIL1,FIL1(ZETA),FIL1Z,IL-1F7,IL-1H,IL-1H4,IL-1RP1,IL-37,IL1F7,IL1H4,IL1RP1,FIL1 zeta,IL 1 zeta,IL 1F7,IL 1F7b (IL 1H4,IL 1H,IL 1H4,IL 1RP1,IL 1RP1),IL 1X,IL 1X protein,IL-1 zeta,IL1F7 (canonical product IL 1F7b),IL-1X,interleukin 1 family,Interleukin 1 family member 7,Interleukin 1 homolog 4,Interleukin 1 related protein,Interleukin 1 superfamily z,Interleukin 1 zeta,Interleukin 37,Interleukin-1 family member 7,Interleukin-1 homolog 4,Interleukin-1
Application:
IHC, WB
Concentration:
1.5 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human IL37
Uniprot:
Q9NZH6
Synonyms:
FIL1;FIL1 zeta;FIL1(ZETA);FIL1Z;IL-1 zeta;IL-1F7;IL-1F7b (IL-1H4, IL-1H, IL-1RP1);IL-1H;IL-1H4;IL-1RP1;IL-1X;IL-1X protein;IL-23;IL-37;IL1F7;IL1F7 (canonical product IL-1F7b);IL1H4;IL1RP1;interleukin 1 family member 7;interleukin 1, zeta;Interleukin-1 family member 7;interleukin-1 homolog 4;interleukin-1 superfamily z;Interleukin-1 zeta;interleukin-1-related protein;interleukin-23;interleukin-37
Extra Details:
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. IL37 (Interleukin 37) is a Protein Coding gene. Diseases associated with IL37 include Rheumatoid Arthritis. Among its related pathways are Innate Immune System and Toll-Like receptor Signaling Pathways. GO annotations related to this gene include cytokine activity and interleukin-1 receptor binding. An important paralog of this gene is IL36G.
Shipping Conditions:
Blue Ice