E-AB-18082
HLA-DPA1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-18082
- Additional Names:
- DP(W3),DP(W4),HLA DP1A,HLA DPA 1,HLA SB alpha chain,HLA class II histocompatibility antigen DP alpha 1 chain,HLA class II histocompatibility antigen DP alpha chain ,HLADP,HLADPA1 ,HLASB,HLASB histocompatibility type,Human MHC class II HLA SB alpha gene,Ma
- Application:
- IHC, WB
- Concentration:
- 0.96 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human HLA-DPA1
- Uniprot:
- P20036
- Synonyms:
- DP(W3);DP(W4);DPA1;HLA class II histocompatibility antigen, DP alpha 1 chain;HLA DPA1;HLA-DP1A;HLA-DPA;HLA-DPA1*01:03:01:New;HLA-DPA1*02:01:01:NEW;HLA-DPB1;HLA-SB alpha chain;HLADP;HLASB;MHC class II antigen DP alpha chain;MHC class II DP alpha chain;MHC class II DP3-alpha;MHC class II DPA1;MHC class II HLA-DPA1 antigen;MHC class II protein;PLT1
- Extra Details:
- HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
- Shipping Conditions:
- Blue Ice