GTF3A Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:: E-AB-18063
Additional Names:: AP 2,AP2,Factor A,GTF 3A,GTF3A,General transcription factor 3A,General transcription factor IIIA,TF3A,TFIIIA,Transcription factor 3A,Transcription factor IIIA
Application:: IHC
Concentration:: 2.22 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Synthetic peptide of human GTF3A
Uniprot:: Q92664
Synonyms:: AP2;TFIIIA;transcription factor IIIA
Extra Details:: The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.