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E-AB-18034

PTGDR2 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-18034
Additional Names:
CD294,CD294 antigen,CRTH 2,CRTH2,Chemoattractant receptor homologous molecule expressed on Th2 cells,Chemoattractant receptor-homologous molecule expressed on Th2 cells,DL1R,DP2 prostaglandin receptor,G Protein Coupled ,chemoattractant receptor-homologous
Application:
IHC
Concentration:
0.78 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human PTGDR2
Uniprot:
Q9Y5Y4
Synonyms:
CD294;chemoattractant receptor homologous molecule expressed on T helper type 2 cells;chemoattractant receptor-homologous molecule expressed on TH2 cells;CRTH2;DL1R;DP2;G-protein coupled receptor 44;GPR44;prostaglandin D2 receptor 2;putative G-protein coupled receptor 44
Extra Details:
This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.PTGDR2 (Prostaglandin D2 Receptor 2) is a Protein Coding gene. Diseases associated with PTGDR2 include Folliculitis and Eosinophilic Pustular Folliculitis. Among its related pathways are Peptide ligand-binding receptors and Ibuprofen Pathway, Pharmacodynamics. GO annotations related to this gene include G-protein coupled receptor activity and prostaglandin F receptor activity. An important paralog of this gene is FPR3.
Shipping Conditions:
Blue Ice