FUT3 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:: E-AB-17979
Additional Names:: Lewis blood group),3/1,4)-fucosyltransferase,Alpha-(1,Blood group Lewis alpha-4-fucosyltransferase,CD174,FT3B,FUT3,FucT III,FucT-III,Fucosyltransferase 3,Fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase,Fucosyltransferase III,Galactoside
Application:: IHC
Concentration:: 1.08 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Synthetic peptide of human FUT3
Uniprot:: P21217
Synonyms:: 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3;alpha-(1,3/1,4)-fucosyltransferase;alpha-3-fucosyltransferase FUT3;blood group Lewis alpha-4-fucosyltransferase;CD174;FT3B;Fucosyltransferase 3;fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group);fucosyltransferase III;FucT-III;galactoside 3(4)-L-fucosyltransferase;LE;Les;Lewis FT;truncated fucosyltransferase 3
Extra Details:: The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.

Shipping Conditions:: Blue Ice