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E-AB-17966

FKBP5 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-17966
Additional Names:
51 kDa FK506 binding protein,51 kDa FK506 binding protein 5,51 kDa FK506-binding protein,51 kDa FKBP,54 kDa progesterone receptor associated immunophilin,54 kDa progesterone receptor-associated immunophilin,AIG 6,AIG6,Androgen,Androgen regulated protein 6
Application:
IHC, WB
Concentration:
1.5 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human FKBP5
Uniprot:
Q13451
Synonyms:
51 kDa FK506-binding protein;51 kDa FKBP;54 kDa progesterone receptor-associated immunophilin;AIG6;androgen-regulated protein 6;FF1 antigen;FK506 binding protein 5;FK506-binding protein 5;FKBP-51;FKBP51;FKBP54;HSP90-binding immunophilin;P54;peptidyl-prolyl cis-trans isomerase FKBP5;peptidylprolyl cis-trans isomerase;PPIase;PPIase FKBP5;Ptg-10;rotamase;T-cell FK506-binding protein
Extra Details:
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice