FBXW8 Polyclonal Antibody

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£106.20

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SKU:: E-AB-17953
Additional Names:: F box and WD40 domain containing protein 8,F box only protein 29,F box/WD repeat containing protein 8,F-box and WD-40 domain-containing protein 8,F-box only protein 29,F-box/WD repeat-containing protein 8,FBW6,FBW8,FBX29,FBXO29,FBXW6,FBXW8
Application:: IHC
Concentration:: 1.92 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Synthetic peptide of human FBXW8
Uniprot:: Q8N3Y1
Synonyms:: F-box and WD-40 domain protein 8;F-box and WD-40 domain-containing protein 8;F-box only protein 29;F-box/WD repeat-containing protein 8;FBW6;FBW8;FBX29;FBXO29;FBXW6
Extra Details:: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

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