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E-AB-17932

FAM213A Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-17932
Additional Names:
C10orf58,CJ058,UPF0765 protein C10orf58
Application:
WB
Concentration:
1.02 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human FAM213A
Uniprot:
Q9BRX8
Synonyms:
Adiporedoxin;Adrx;C10orf58;FAM213A;family with sequence similarity 213 member A;PAMM;peroxiredoxin (PRX)-like 2 activated in M-CSF stimulated monocytes;peroxiredoxin-like 2 activated in M-CSF stimulated monocytes;peroxiredoxin-like 2A;redox-regulatory protein FAM213A;redox-regulatory protein PAMM;UPF0765 protein C10orf58
Extra Details:
Involved in redox regulation of the cell.Acts as an antioxidant. Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation. May affect bone resorption and help to maintain bone mass. Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway.
Shipping Conditions:
Blue Ice