E-AB-17923
EPS15 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-17923
- Additional Names:
- AF 1P,AF 1p protein,AF1P,ALL1 fused gene from chromosome 1,EPS 15,Epidermal growth factor receptor pathway substrate 15,Epidermal growth factor receptor substrate 15,MLLT 5,MLLT5,Protein Eps 15,Protein Eps15
- Application:
- IHC
- Concentration:
- 1.5 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human EPS15
- Uniprot:
- P42566
- Synonyms:
- AF-1P;AF1P;ALL1 fused gene from chromosome 1;epidermal growth factor receptor substrate 15;MLLT5;protein AF-1p
- Extra Details:
- This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15) is a Protein Coding gene. Diseases associated with EPS15 include Vaccinia. Among its related pathways are Notch signaling pathway (KEGG) and HIV Life Cycle. GO annotations related to this gene include calcium ion binding and SH3 domain binding. An important paralog of this gene is EPS15L1.
- Shipping Conditions:
- Blue Ice