E-AB-17896
DUSP27 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-17896
- Additional Names:
- C130085G02Rik,DUS27,DUSP27,Gm209,Inactive dual specificity phosphatase 27,RGD1560598
- Application:
- IHC
- Concentration:
- 1.92 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human DUSP27
- Uniprot:
- Q5VZP5
- Synonyms:
- dual specificity phosphatase 27 (putative);dual specificity phosphatase 27, atypical;DUSP27;inactive dual specificity phosphatase 27;serine/threonine/tyrosine-interacting-like protein 2
- Extra Details:
- Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members, including MAPK/ERK, SAPK/JNK and p38. DUSP27 (dual specificity phosphatase 27), also known as FMDSP or DUPD1 (dual specificity phosphatase and pro isomerase domain containing 1), is a 220 amino acid cytoplasmic protein that belongs to the protein-tyrosine phosphatase family. Expressed in skeletal muscle, liver and adipose tissue, DUSP27 may play a role in energy metabolism. The gene encoding DUSP27 is referred to as DUPD1 and maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome.
- Shipping Conditions:
- Blue Ice