E-AB-17889
DMGDH Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-17889
- Additional Names:
- Dimethylglycine dehydrogenase,Dmgdh,M2GD,ME2GLYDH,mitochondrial
- Application:
- WB
- Concentration:
- 2.1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human DMGDH
- Uniprot:
- Q9UI17
- Synonyms:
- dimethylglycine dehydrogenase, mitochondrial;DMGDHD;ME2GLYDH
- Extra Details:
- This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.
- Shipping Conditions:
- Blue Ice