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E-AB-17823

PIAS3 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-17823
Additional Names:
E3 SUMO protein ligase PIAS 3,E3 SUMO protein ligase PIAS3,E3 SUMO-protein ligase PIAS3,FLJ14651,OTTHUMP00000015586,OTTHUMP00000015587,PIAS 3,PIAS3,PIAS3 protein,Pias3,Pro,Protein inhibitor of activated STAT 3,Protein inhibitor of activated STAT protein 3
Application:
IHC
Concentration:
1.1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human PIAS3
Uniprot:
Q9Y6X2
Synonyms:
E3 SUMO-protein ligase PIAS3;E3 SUMO-protein transferase PIAS3;protein inhibitor of activated STAT protein 3;zinc finger, MIZ-type containing 5;ZMIZ5
Extra Details:
This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.
Shipping Conditions:
Blue Ice