E-AB-17759
CAD Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-17759
- Additional Names:
- Aspartate carbamoyltransferase,Aspartate transcarbamylase,CAD protein,CAD trifunctional protein,CPSase ATCase DHOase,Carbamoyl phosphate synthetase 2,Carbamoyl-phosphate synthetase 2 aspartate transcarbamylase and dihydroorotase,Dihydroorotase,Glutamine d
- Application:
- IHC
- Concentration:
- 0.7 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human CAD
- Uniprot:
- P27708
- Synonyms:
- CAD protein;CAD trifunctional protein;CDG1Z;DEE50;EIEE50;GATD4;multifunctional protein CAD
- Extra Details:
- The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Shipping Conditions:
- Blue Ice