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E-AB-17744

C16orf45 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-17744
Additional Names:
C16orf45,CP045,Chromosome 16 open reading frame 45,FLJ32618,Uncharacterized protein C16orf45,Uncharacterized protein C16orf45 homolog
Application:
IHC
Concentration:
0.7 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human C16orf45
Uniprot:
Q96MC5
Synonyms:
bMERB domain-containing protein 1;C16orf45;migration inhibitory protein;MINP;uncharacterized protein C16orf45
Extra Details:
C16orf45, also known as FLJ32618, is a 204 amino acid protein encoded by a gene mapping to human chromosome 16. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.
Shipping Conditions:
Blue Ice