E-AB-17625
SLC7A11 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-17625
- Additional Names:
- Amino acid transport system xc xCT,Amino acid transport system xc-,CCBR1,Calcium channel blocker resistance protein CCBR1,Cysteine/glutamate transporter,Cystine/glutamate transporter,OTTHUMP00000164578,SLC7
- Application:
- IHC
- Concentration:
- 0.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human SLC7A11
- Uniprot:
- Q9UPY5
- Synonyms:
- amino acid transport system xc-;calcium channel blocker resistance protein CCBR1;CCBR1;cystine/glutamate transporter;solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11;Solute carrier family 7 member 11;solute carrier family 7, (cationic amino acid transporter, y+ system) member 11;xCT
- Extra Details:
- This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.
- Shipping Conditions:
- Blue Ice