E-AB-17347
LRP6 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-17347
- Additional Names:
- ADCAD2,C030016K15Rik,Cd,FLJ90062,FLJ90421,LDL receptor related protein 6,LRP-6,LRP6,Low density lipoprotein receptor related protein 6,Low-density lipoprotein receptor-related protein 6,OTTHUMP00000238979,OTTHUMP00000238980,OTTHUMP00000238982,STHAG7
- Application:
- IHC
- Concentration:
- 1.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human LRP6
- Uniprot:
- O75581
- Synonyms:
- ADCAD2;low-density lipoprotein receptor-related protein 6;LRP-6;STHAG7
- Extra Details:
- This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
- Shipping Conditions:
- Blue Ice