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E-AB-17184

UACA Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-17184
Additional Names:
FLJ10128,KIAA1561,MGC141967,MGC141969,NUCLING,Nuclear membrane binding protein,UACA,Uveal autoantigen with coiled coil domains and ankyrin repeats,Uveal autoantigen with coiled-coil domains and ankyrin repeats
Application:
IHC
Concentration:
0.8 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Fusion protein of human UACA
Uniprot:
Q9BZF9
Synonyms:
nuclear membrane binding protein;NUCLING;uveal autoantigen with coiled-coil domains and ankyrin repeats
Extra Details:
Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity).
Shipping Conditions:
Blue Ice